Surgery Godfather

Chapter 2241: Chapter 1459: Just to Share the Good News

The news of the success of the surgery for excrescence reconstruction spread through the Thoracic Surgery Department faster than the flu.

Early the next morning, as Yang Ping was entering the institute building, he saw Director He standing by the elevator, his face showing an expression Yang had never seen before. If he had to describe it, it resembled the smile of a top scorer who just checked his college entrance examination results.

"Professor Yang!" As soon as Director He saw Yang Ping, his eyes lit up, "The patient was very stable last night, with less than one hundred milliliters of drainage. This morning’s chest X-ray recheck showed good lung expansion with no leakage at the anastomosis site."

"So you came specifically to tell me this?" Yang Ping pressed the elevator button.

"Yes, I’ve been waiting here for half an hour." Director He did not enter the elevator either.

"You’re not coming in?"

"No, I need to go back and host the shift handover."

Yang Ping found this guy strange, waiting by the elevator just to say this sentence.

Returning to the office, Yang Ping opened his laptop to check for any new emails.

There weren’t many emails, only a dozen or so. Most were manuscript review invitations from academic journals and a few conference abstract submissions. He quickly scanned them and directly rejected several review invitations that clearly did not fit his research direction, leaving the rest to handle in the afternoon.

He stood up, exited the office, and decided to take a tour of the laboratory. Though he called it a tour, it was basically walking around, chatting with students, and understanding the progress of experiments. This informal conversation is often more effective than formal group meetings, as students tend to express things in a relaxed atmosphere that they might not dare to speak about in formal settings.

In the cell laboratory, Manstein was leading two students in cell culture. He wore a cultural shirt printed with "I️ Science", his hair as messy as a bird’s nest, holding a pipette, looking focused like he was defusing a bomb.

Yang Ping didn’t interrupt him and stood at the door watching for a while.

Manstein’s operation was as precise as ever; pipetting, sampling, mixing, centrifuging—all actions were fluid and like a carefully choreographed dance.

"Professor?" Manstein looked up after completing the final step and saw Yang Ping, "Why are you standing at the door? Come in."

"Afraid of disturbing you." Yang Ping walked in, "What are you doing today?"

"Validation of the function of unknown factors." Manstein wiped his hands and took a Petri dish from the incubator, "Look at this, this neuron added with the recombinant unknown factor, with very good differentiation, the axon length is twice that of the control group. If we can confirm it’s this protein at work, the value of this paper would be immeasurable."

Yang Ping took the Petri dish and observed under the microscope. The morphology of the neurons was indeed excellent; the cell body was full and round, with axons and dendrites extending long and straight, like thriving small trees.

"Recombinant protein purified?" Yang Ping asked.

"Yes, we’ve used an Escherichia coli expression system, and the purity of the purified protein is over ninety-five percent." Manstein said, "Weber is doing a co-culture experiment with stem cells using this protein, and if the results are also positive, then the function can basically be confirmed."

"Proteins expressed by Escherichia coli might not be completely consistent in structure and function with natural proteins." Yang Ping reminded, "You’d better do a mammalian cell expression as a parallel verification."

"We are already working on it." Manstein said, "HEK293 cell expression system, purification progress about sixty percent, should be completed next week."

Yang Ping nodded and returned the Petri dish to Manstein.

"By the way, Professor." Manstein suddenly lowered his voice, "Did you look at Weber’s experiment on temperature exposure time?"

"Yes, Tang Shun told me about it."

"Don’t you find it interesting?" Manstein’s eyes lit up, "The first two hours after cell seeding is the window period for the cells to recover from frozen storage to normal state. During this window period, cells have the strongest ability to respond to external signals. What does this imply? It implies the methods we used in cell experiments might have always been wrong; we have always done drug treatment after cells adhere to the surface, but actually, the best drug administration time might be when the cells are just seeded."

"You mean many drugs in cell experiments have been underestimated in effect?"

"Yes! Because we administered at the wrong time."

Yang Ping thought for a moment and felt Manstein made sense. Although this discovery seems small, the implications could be broad. If proven to have general applicability, many experiments in cell biology might need to be reevaluated.

"You could collaborate with Weber to write a review, systematically organize this issue, propose a hypothesis, and use your experimental data to support it. Such a review might be widely cited."

Manstein nodded and noted it down in his notebook.

At two in the afternoon, the institute’s weekly meeting started on time.

The meeting room was crowded as usual. Tang Shun sat to Yang Ping’s left, jotting notes in his notebook. Lu Xiaolu sat on the right, with a laptop spread out in front of him. Manstein, Weber, Jiang Jitong, and a few new group leaders each occupied a corner of the meeting table. Their students and postdocs sat in the back row, some seriously reading materials, some secretly browsing their phones.

Yang Ping glanced at everyone and cleared his throat.

"Let’s begin."

The first to report was Tang Shun. He stood up, walked to the projection screen, and opened a PPT.

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